{"id":40346,"date":"2016-12-10T21:26:21","date_gmt":"2016-12-10T20:26:21","guid":{"rendered":"http:\/\/www.revista-portalesmedicos.com\/revista-medica\/?p=40346"},"modified":"2016-12-10T21:26:21","modified_gmt":"2016-12-10T20:26:21","slug":"metastasis-carcinoma-laringe","status":"publish","type":"post","link":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/metastasis-carcinoma-laringe\/","title":{"rendered":"Met\u00e1stasis inusual de un carcinoma de laringe"},"content":{"rendered":"

Met\u00e1stasis inusual de un carcinoma de laringe<\/strong><\/h1>\n

Introducci\u00f3n:<\/strong><\/p>\n

Las met\u00e1stasis a distancia de los carcinomas lar\u00edngeos son raras. En el momento del diagn\u00f3stico son tan s\u00f3lo del 0,5% seg\u00fan algunas series. Cuando aparecen las met\u00e1stasis suelen detectarse preferentemente en pulm\u00f3n y hueso. Las met\u00e1stasis a la hip\u00f3fisis del Carcinoma de laringe son extremadamente infrecuentes y existen muy pocos casos descritos en la literatura.<\/p>\n

<\/p>\n

Met\u00e1stasis inusual de un carcinoma de laringe<\/strong><\/p>\n

Autores:<\/strong><\/p>\n

Nicol\u00e1s Fern\u00e1ndez Fern\u00e1ndez 1<\/sup><\/p>\n

Maria de Alharilla Montilla Ib\u00e1\u00f1ez 1<\/sup><\/p>\n

Alberto Jos\u00e9 N\u00fa\u00f1ez Ram\u00edrez 1<\/sup><\/p>\n

Juan Ignacio Santaella S\u00e1ez 2<\/sup><\/p>\n

1.- FEA ORL Hospital La Inmaculada, Hu\u00e9rcal-Overa, (Almer\u00eda).<\/p>\n

2.- FEA ORL Complejo Hospitalario de Granada.<\/p>\n

Material y m\u00e9todos:<\/strong><\/p>\n

Mujer de 58 a\u00f1os intervenida por carcinoma lar\u00edngeo realiz\u00e1ndose una laringectom\u00eda total con doble vaciamiento m\u00e1s quimiorradioterapia. Un a\u00f1o m\u00e1s tarde de la intervenci\u00f3n, la paciente comienza con cefaleas que no cede con tratamiento analg\u00e9sico. Adem\u00e1s refiere diplop\u00eda con la mirada extrema hacia la derecha (par\u00e1lisis del VI par).<\/p>\n

Se le realiz\u00f3 una Resonancia Magn\u00e9tica (figuras 1 y 2) que muestra lesi\u00f3n sellar de 4 cm, homog\u00e9nea, que invade y destruye estructuras adyacentes.<\/p>\n

Estudio hormonal: hiperprolactinemia, descenso hormonas tiroideas y elevaci\u00f3n de TSH.<\/p>\n

Estudio campim\u00e9trico: normal<\/p>\n

Se le realiz\u00f3 una biopsia transnasal-transesfenoidal con resultado de met\u00e1stasis de carcinoma epidermoide pobremente diferenciado.<\/p>\n

PET-TAC: foco hipermetab\u00f3lico en hip\u00f3fisis compatible con met\u00e1stasis conocida. Resto del rastreo corporal sin hallazgos patol\u00f3gicos.<\/p>\n

Resultados\/Conclusiones:<\/strong><\/p>\n

La evoluci\u00f3n despu\u00e9s de la cirug\u00eda para la biopsia fue satisfactoria. Actualmente est\u00e1 en tratamiento con radioterapia.<\/p>\n

Las met\u00e1stasis a distancia de los carcinomas de laringe ensombrecen bastante el pron\u00f3stico. As\u00ed mismo, las met\u00e1stasis a distancia pueden aparecer con posterioridad a un tratamiento que ha conseguido el control locorregional correcto.<\/p>\n

Lo curioso de este caso es que las met\u00e1stasis del c\u00e1ncer de laringe suelen ser hacia los ganglios linf\u00e1ticos locorregionales y ocasionalmente hacia el pulm\u00f3n. Ya m\u00e1s raro son las met\u00e1stasis hacia los huesos y a\u00fan m\u00e1s inusual hacia el h\u00edgado. Pero s\u00ed que apenas hay publicado en la literatura met\u00e1stasis a hip\u00f3fisis procedente de un c\u00e1ncer de laringe. M\u00e1s a\u00fan, cuando las met\u00e1stasis desde cualquier sitio hacia la hip\u00f3fisis ya son bastante poco frecuentes.<\/p>\n

Figura 1: Resonancia magn\u00e9tica cerebral en corte sagital donde se visualiza la masa en regi\u00f3n selar.<\/p>\n

\"metastasis-resonancia-magnetica-cerebral-sagital\"<\/a>
Met\u00e1stasis. Resonancia magn\u00e9tica cerebral sagital<\/figcaption><\/figure>\n

Figura 2: Resonancia magn\u00e9tica en corte axial con tumoraci\u00f3n resaltada con el contraste intravenoso.<\/p>\n

\"metastasis-resonancia-magnetica-cerebral-axial\"<\/a>
Met\u00e1stasis. Resonancia magn\u00e9tica cerebral axial<\/figcaption><\/figure>\n

BIBLIOGRAF\u00cdA:<\/strong><\/p>\n

Quer Agust\u00ed, M & L\u00f3pez Vila, M. (2008). Caracter\u00edsticas cl\u00ednicas de los tumores de la laringe. En: Su\u00e1rez, C. Gil-Carcedo, JE. Marco, J. Medina, JE. Ortega, P. Trinidad, J. (Ed.), Tratado de Otorrinolaringolog\u00eda y Cirug\u00eda de Cabeza y Cuello (2\u00aa ed, pp.3522-3523). Madrid, Espa\u00f1a: Editorial M\u00e9dica Panamericana.<\/p>\n

Uzal MC1, Kocak Z, Doganay L, Tokatli F, Caloglu M, Kilincer C. Pituitary metastasis mimicking a macroadenoma from carcinoma of the larynx: a case report. Tumori. 2001 Nov-Dec;87(6):451-4.<\/p>\n

Lahoz Zamarro MT, Galve Royo F, Mart\u00ednez Subias J, Lagu\u00eda P\u00e9rez M. Met\u00e1stasis a distancia en pacientes con carcinoma de laringe avanzado. Acta Otorrinolaringol Esp 2001; 52: 307-311<\/p>\n","protected":false},"excerpt":{"rendered":"

Met\u00e1stasis inusual de un carcinoma de laringe Introducci\u00f3n: Las met\u00e1stasis a distancia de los carcinomas lar\u00edngeos son raras. En el momento del diagn\u00f3stico son tan s\u00f3lo del 0,5% seg\u00fan algunas series. Cuando aparecen las met\u00e1stasis suelen detectarse preferentemente en pulm\u00f3n y hueso. Las met\u00e1stasis a la hip\u00f3fisis del Carcinoma de laringe son extremadamente infrecuentes y … <\/p>\n

Leer m\u00e1s<\/a><\/p>\n","protected":false},"author":2,"featured_media":40348,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[180],"tags":[8337,1171],"class_list":["post-40346","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-otorrinolaringologia","tag-carcinoma-de-laringe","tag-metastasis","no-featured-image-padding"],"acf":[],"yoast_head":"\nMet\u00e1stasis inusual de un carcinoma de laringe<\/title>\n<meta name=\"description\" content=\"Met\u00e1stasis inusual de un carcinoma de laringe Introducci\u00f3n: Las met\u00e1stasis a distancia de los carcinomas lar\u00edngeos son raras. 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