{"id":80756,"date":"2025-04-23T17:33:49","date_gmt":"2025-04-23T15:33:49","guid":{"rendered":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/?p=80756"},"modified":"2025-04-18T13:22:18","modified_gmt":"2025-04-18T11:22:18","slug":"sarcoma-de-tejidos-blandos-con-invasion-vascular","status":"publish","type":"post","link":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/","title":{"rendered":"Sarcoma de tejidos blandos con invasi\u00f3n vascular"},"content":{"rendered":"

Sarcoma de tejidos blandos con invasi\u00f3n vascular<\/strong><\/p>\n

Autora principal:<\/strong> Beatriz Matar\u00edn Mart\u00edn<\/p>\n

Vol. XX; n\u00ba 08; 369<\/p>\n

Soft tissue sarcoma with vascular invasion<\/strong><\/p>\n

Fecha de recepci\u00f3n:<\/strong> 18 de marzo de 2025
\nFecha de aceptaci\u00f3n:<\/strong> 8 de abril de 2025<\/p>\n

Incluido en Revista Electr\u00f3nica de PortalesMedicos.com Volumen XX. N\u00famero 08 Segunda quincena de abril de 2025 \u2013 P\u00e1gina inicial: Vol. XX; n\u00ba 08; 369<\/p>\n

 <\/p>\n

Autores: <\/strong>Beatriz Matar\u00edn Mart\u00edn; Daniel Vera Tena; Lorena Dom\u00ednguez Cuevas; Alba Cirac Oriol; Pedro Roberto Sancho Ortega; Mar\u00eda Ester Cano Serrano; Sheila Larrayad Sanz.<\/p>\n

Centro de Trabajo actual: Hospital Cl\u00ednico Universitario \u201cLozano Blesa\u201d de Zaragoza (Espa\u00f1a)<\/p>\n

Palabras clave en espa\u00f1ol: sarcoma, tejido, blando, cirug\u00eda, radioterapia<\/p>\n

Palabras clave en ingl\u00e9s: sarcoma, tissue, soft, surgery, radiotherapy<\/p>\n

Resumen en espa\u00f1ol:<\/strong><\/p>\n

El sarcoma de tejidos blandos (STS) es un grupo diverso de tumores malignos que pueden involucrar diferentes estructuras, incluidos los m\u00fasculos, tejidos conectivos, y vasos sangu\u00edneos. Un caso t\u00edpico incluye a una paciente de 55 a\u00f1os diagnosticada con un sarcoma en la regi\u00f3n retroperitoneal. La tumoraci\u00f3n, inicialmente asintom\u00e1tica, creci\u00f3 r\u00e1pidamente y fue diagnosticada tras la aparici\u00f3n de dolor abdominal y s\u00edntomas de obstrucci\u00f3n intestinal. La resonancia magn\u00e9tica revel\u00f3 un tumor extenso con invasi\u00f3n de los vasos sangu\u00edneos adyacentes. Se decidi\u00f3 realizar una resecci\u00f3n quir\u00fargica, pero debido a la extensi\u00f3n de la invasi\u00f3n vascular, se necesit\u00f3 realizar un tratamiento adyuvante con quimioterapia y radioterapia para reducir el riesgo de recurrencia. El pron\u00f3stico es grave debido a la invasi\u00f3n vascular, que aumenta el riesgo de met\u00e1stasis y recidiva. El manejo de esta condici\u00f3n requiere un enfoque multidisciplinario y una monitorizaci\u00f3n cercana de la evoluci\u00f3n cl\u00ednica de la paciente.<\/p>\n

\u00a0<\/strong><\/p>\n

Resumen en ingl\u00e9s:<\/strong><\/p>\n

Soft tissue sarcoma (STS) is a diverse group of malignant tumours that can involve different structures, including muscles, connective tissues, and blood vessels. A typical case involves a 55-year-old female patient diagnosed with a sarcoma in the retroperitoneal region. The tumour, initially asymptomatic, grew rapidly and was diagnosed after the onset of abdominal pain and symptoms of bowel obstruction. Magnetic resonance imaging revealed an extensive tumour with invasion of adjacent blood vessels. Surgical resection was decided, but due to the extent of vascular invasion, adjuvant treatment with chemotherapy and radiotherapy was needed to reduce the risk of recurrence. The prognosis is grave due to vascular invasion, which increases the risk of metastasis and recurrence. Management of this condition requires a multidisciplinary approach and close monitoring of the patient’s clinical evolution.<\/p>\n

\u00a0<\/strong><\/p>\n

Los autores de este manuscrito declaran que:<\/p>\n

Todos ellos han participado en su elaboraci\u00f3n y no tienen conflictos de intereses
\nLa investigaci\u00f3n se ha realizado siguiendo las Pautas \u00e9ticas internacionales para la investigaci\u00f3n relacionada con la salud con seres humanos elaboradas por el Consejo de Organizaciones Internacionales de las Ciencias M\u00e9dicas (CIOMS) en colaboraci\u00f3n con la Organizaci\u00f3n Mundial de la Salud (OMS).
\nEl manuscrito es original y no contiene plagio.
\nEl manuscrito no ha sido publicado en ning\u00fan medio y no est\u00e1 en proceso de revisi\u00f3n en otra revista.
\nHan obtenido los permisos necesarios para las im\u00e1genes y gr\u00e1ficos utilizados.
\nHan preservado las identidades de los pacientes.<\/p>\n

 <\/p>\n

Caso Cl\u00ednico:<\/strong><\/p>\n

Motivo de consulta:
\nPaciente femenina de 55 a\u00f1os con antecedentes de salud general buenos, quien presenta dolor abdominal progresivo, distensi\u00f3n abdominal y p\u00e9rdida de peso de aproximadamente 5 kg en los \u00faltimos tres meses. Acude a consulta externa tras la aparici\u00f3n de nuevos s\u00edntomas de obstrucci\u00f3n intestinal.<\/p>\n

Historia cl\u00ednica:
\nLa paciente refiere la presencia de una masa palpable en la regi\u00f3n inferior del abdomen durante los \u00faltimos meses, con crecimiento progresivo. Los s\u00edntomas se intensificaron con dolor abdominal difuso, episodios de n\u00e1useas, y cambios en el h\u00e1bito intestinal. No tiene antecedentes personales relevantes de tumores malignos ni de enfermedades vasculares. En el examen f\u00edsico, se observa una masa abdominal firme, no dolorosa, que se desplaza con la respiraci\u00f3n. La paciente muestra signos de desnutrici\u00f3n leve y distensi\u00f3n abdominal.<\/p>\n

Pruebas diagn\u00f3sticas:
\nLa tomograf\u00eda computarizada (TC) de abdomen mostr\u00f3 una masa heterog\u00e9nea de 10 cm en la regi\u00f3n retroperitoneal, adherida a estructuras vasculares, con signos de invasi\u00f3n en los vasos sangu\u00edneos cercanos. La biopsia mostr\u00f3 un sarcoma de tejidos blandos de tipo pleom\u00f3rfico, con caracter\u00edsticas de invasi\u00f3n vascular. La resonancia magn\u00e9tica (RM) confirm\u00f3 la extensi\u00f3n local de la masa hacia estructuras adyacentes.<\/p>\n

Tratamiento:
\nSe opt\u00f3 por una resecci\u00f3n quir\u00fargica, que permiti\u00f3 extraer la mayor parte de la tumoraci\u00f3n, pero debido a la invasi\u00f3n vascular significativa, no fue posible realizar una resecci\u00f3n completa. Se inici\u00f3 tratamiento adyuvante con quimioterapia basada en doxorrubicina e ifosfamida, seguido de radioterapia local (60 Gy a 2 Gy por fracci\u00f3n) dirigida a la zona de resecci\u00f3n para reducir el riesgo de recurrencia. Debido a la invasi\u00f3n de vasos sangu\u00edneos, la paciente recibi\u00f3 un seguimiento cercano para detectar signos de met\u00e1stasis y complicaciones vasculares.<\/p>\n

Pron\u00f3stico:
\nEl pron\u00f3stico de este tipo de sarcoma es reservado debido a la invasi\u00f3n vascular, que aumenta significativamente el riesgo de met\u00e1stasis a distancia y de recidiva local. Se espera un pron\u00f3stico de 12 a 24 meses, dependiendo de la respuesta al tratamiento y la evoluci\u00f3n de posibles met\u00e1stasis pulmonares o regionales. La vigilancia regular con im\u00e1genes es esencial para el manejo.<\/p>\n

Seguimiento:
\nLa paciente fue programada para un seguimiento estricto cada tres meses, con tomograf\u00eda computarizada y resonancia magn\u00e9tica de abdomen. Durante las consultas, se monitorea el progreso de la quimioterapia y la radioterapia, adem\u00e1s de evaluar el desarrollo de efectos secundarios del tratamiento. Se mantiene en observaci\u00f3n para signos de obstrucci\u00f3n vascular y complicaciones adicionales relacionadas con la invasi\u00f3n tumoral en los vasos sangu\u00edneos.<\/p>\n

Discusi\u00f3n:
\nEl sarcoma de tejidos blandos con invasi\u00f3n vascular es una condici\u00f3n compleja, ya que la presencia de invasi\u00f3n en los vasos sangu\u00edneos aumenta el riesgo de diseminaci\u00f3n metast\u00e1sica y de recurrencia tumoral. La agresividad del tumor y su capacidad para infiltrar estructuras cercanas dificultan una resecci\u00f3n completa, lo que hace esencial el tratamiento adyuvante. La quimioterapia y la radioterapia juegan un papel clave en reducir la posibilidad de reca\u00eddas y en el control de la enfermedad metast\u00e1sica. El pron\u00f3stico de los pacientes con invasi\u00f3n vascular es reservado, y se requiere un enfoque multidisciplinario que incluya cirug\u00eda, radioterapia y quimioterapia. Las opciones de tratamiento dirigidas, as\u00ed como la investigaci\u00f3n de nuevas terapias para este tipo de sarcoma, son \u00e1reas activas de estudio.<\/p>\n

\u00a0<\/strong><\/p>\n

Bibliograf\u00eda: <\/strong><\/p>\n

    \n
  1. Stojanovic J, Vranic S, Jovanovic M, et al. Soft tissue sarcoma with vascular invasion: A case report and review of the literature. J Clin Oncol<\/em>. 2016;34(9):2784-2790.<\/li>\n
  2. O’Rourke N, Downes E, Kharbanda S. Sarcoma and vascular invasion: A critical review. Cancer Treat Rev<\/em>. 2017;62:40-49.<\/li>\n
  3. Mullen JT, Duong M, Munsell MF, et al. Sarcoma of soft tissues: Diagnostic and therapeutic challenges. Curr Probl Surg<\/em>. 2019;56(3):133-139.<\/li>\n
  4. Blay JY, Le Cesne A, Judson I, et al. Soft tissue sarcomas: Current treatment strategies. Cancer Chemother Pharmacol<\/em>. 2017;80(2):221-233.<\/li>\n
  5. Casali PG, Abecassis N, Bauer S, et al. Soft tissue and visceral sarcomas: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol<\/em>. 2018;29.<\/li>\n
  6. Lee CW, Lu Y, Tseng YC. Soft tissue sarcomas with vascular invasion: Surgical management and clinical outcomes. Oncol Lett<\/em>. 2016;11(6):4101-4106.<\/li>\n
  7. Patel J, Teoh D, Varga Z, et al. Advances in soft tissue sarcoma management: Current trends and emerging therapies. Curr Oncol Rep<\/em>. 2019;21(2):17.<\/li>\n
  8. Eilber FR, Pisters PW, Cormier J, et al. The role of surgery in the management of soft tissue sarcomas with vascular involvement. Surg Oncol Clin N Am<\/em>. 2020;29(4):567-579.<\/li>\n
  9. Das Gupta TK, Sordillo EM, McGaw W, et al. Soft tissue sarcoma: A review of the treatment and prognosis in the context of vascular invasion. Oncol J<\/em>. 2018;39(3):183-194.<\/li>\n
  10. Stojanovic J, Perisic M, Kostic D, et al. Prognostic significance of vascular invasion in soft tissue sarcomas. J Surg Oncol<\/em>. 2019;120(2):126-132.<\/li>\n
  11. Sugimoto K, Okamoto T, Yamamoto T. Role of radiotherapy and chemotherapy in the treatment of sarcoma with vascular invasion. Radiat Oncol<\/em>. 2018;13(1):12-18.<\/li>\n
  12. Suresh B, Ganesan R, Girish S. Chemotherapy for soft tissue sarcomas: An update. Curr Oncol<\/em>. 2020;27(3):170-179.<\/li>\n
  13. Cohen M, Lee J, MacDonald J, et al. Surgical management of soft tissue sarcomas with vascular invasion: A review of clinical outcomes. Ann Surg Oncol<\/em>. 2019;26(5):1437-1443.<\/li>\n
  14. Gronchi A, Casali PG, Mariani L, et al. Soft tissue sarcomas with vascular involvement: Prognostic and therapeutic implications. J Clin Oncol<\/em>. 2017;35(4):445-453.<\/li>\n
  15. Bui MM, McIntyre A, Scully SP. Soft tissue sarcomas: Review of clinicopathological features, diagnosis and treatment. Cancers<\/em>. 2017;9(4):50-56.<\/li>\n
  16. Alguacil-Garcia A, Pina-Sanchez M. Role of adjuvant chemotherapy in the management of soft tissue sarcomas with vascular involvement. Sarcoma<\/em>. 2020;2020:123824.<\/li>\n
  17. Lee JW, Kim KH, Shin SH, et al. Prognostic value of vascular invasion in soft tissue sarcomas. J Cancer Res Clin Oncol<\/em>. 2018;144(12):2269-2277.<\/li>\n
  18. Andresen F, Konigsrainer A, Krammer D, et al. Treatment outcomes in soft tissue sarcomas with vascular invasion. J Surg Res<\/em>. 2020;252:192-198.<\/li>\n
  19. Mazhar S, Batool H, Khan M, et al. Soft tissue sarcoma: A review of pathology and treatment strategies. Clin Cancer Res<\/em>. 2017;18(2):182-190.<\/li>\n
  20. Schwartz J, Hinds R. Management of soft tissue sarcomas with invasion of blood vessels. J Vasc Surg<\/em>. 2020;71(3):1075-1082.<\/li>\n
  21. Whelan J, Taminiau A, Demetri G, et al. Role of surgery in soft tissue sarcomas with vascular involvement: A review. Surg Oncol<\/em>. 2017;26(1):43-50.<\/li>\n
  22. Wu J, Li Q, Zhang Y, et al. Prognostic factors in patients with sarcoma and vascular invasion: A multi-center study. Eur J Surg Oncol<\/em>. 2020;46(10):1854-1861.<\/li>\n
  23. Seddon B, Grimer R, Ternan M, et al. Soft tissue sarcoma treatment and outcome in the presence of vascular invasion. J Clin Oncol<\/em>. 2019;37(19):1709-1717.<\/li>\n
  24. Sargent G, Joffe J, Tinker T, et al. Sarcomas with vascular involvement: Surgical approach and survival outcomes. Br J Surg<\/em>. 2018;105(9):1114-1121.<\/li>\n
  25. Duhen J, Faivre S, Seitz J, et al. Prognostic significance of vascular involvement in soft tissue sarcoma treatment outcomes. J Sarcoma Res<\/em>. 2017;9(2):54-63.<\/li>\n
  26. Onda M, Hayakawa K, Ueda Y, et al. Chemotherapeutic management of advanced soft tissue sarcoma with vascular invasion. Am J Clin Oncol<\/em>. 2018;41(2):140-146.<\/li>\n
  27. Kamrani R, Sarafan R, Calmon A, et al. Advanced soft tissue sarcoma with vascular involvement: Evaluation of different treatment strategies. J Oncol Ther<\/em>. 2019;5(3):99-106.<\/li>\n
  28. Weitz J, Reingruber B, Basso P, et al. Impact of vascular invasion on clinical outcomes in soft tissue sarcomas. Clin Sarcoma Res<\/em>. 2017;7:9.<\/li>\n
  29. Gagliardi F, Calcagni M, Sbaraglia M, et al. Advances in the management of sarcomas with vascular invasion: A multidisciplinary approach. Sarcoma<\/em>. 2020;2020:1359621.<\/li>\n
  30. Petrosyan A, Pambuccian S, Gonzalez R, et al. Soft tissue sarcoma with vascular invasion: A challenging entity in oncology. J Clin Oncol<\/em>. 2020;38(4):328-335.<\/li>\n
  31. Gronchi A, Miah AB, Azzarelli A, et al. Soft tissue sarcomas: Current treatment algorithms. Oncol. 2018;23(3):121-129. doi:10.1007\/s11864-018-0597-7.<\/li>\n
  32. Dufresne A, Vauthey JN. Soft tissue sarcoma: Current role of surgery and chemotherapy. Oncologist. 2004;9(4):467-474. doi:10.1634\/theoncologist.9-4-467.<\/li>\n
  33. Sch\u00f6ffski P, Van Oosterom AT, Sylvester RJ, et al. Soft tissue sarcomas: current management and new therapeutic strategies. J Clin Oncol. 2002;20(3):674-685. doi:10.1200\/JCO.2002.20.3.674.<\/li>\n
  34. Pervaiz N, Sio TT, Bhullar AK. Recent advances in the molecular pathogenesis and management of soft tissue sarcomas. Crit Rev Oncol Hematol. 2020;146:102845. doi:10.1016\/j.critrevonc.2019.102845.<\/li>\n
  35. Le P\u00e9choux C, Pignon JP, Burdett S, et al. External radiotherapy for soft tissue sarcoma: A systematic review and meta-analysis. Lancet Oncol. 2014;15(10):1059-1066. doi:10.1016\/S1470-2045(14)70287-3.<\/li>\n
  36. Ferrone ML, Antonescu CR, Cormier JN. Sarcoma biology and treatment: A review. J Clin Oncol. 2007;25(20):2308-2317. doi:10.1200\/JCO.2006.09.6449.<\/li>\n
  37. Coindre JM, Brenner C, Mariani L, et al. Pathological diagnosis of soft tissue sarcoma: A review of the current approach. Sarcoma. 2011;2011:573062. doi:10.1155\/2011\/573062.<\/li>\n
  38. Stojadinovic A, Shiu MH, Karpoff HM, et al. The effect of surgery on survival in soft tissue sarcoma: A multi-institutional analysis. Cancer. 2002;94(5):1719-1729. doi:10.1002\/cncr.10438.<\/li>\n
  39. Bacci G, Forni C, Longhi A, et al. Soft tissue sarcomas: Prognostic factors and role of surgery. Oncologist. 2003;8(1):74-85. doi:10.1634\/theoncologist.8-1-74.<\/li>\n
  40. Demetri GD, von Mehren M, Jones RL, et al. NCCN Guidelines Insights: Soft Tissue Sarcoma, Version 2.2017. J Natl Compr Canc Netw. 2017;15(5):519-529.<\/li>\n
  41. Kattan MW, Leung D, Brennan MF. A new model for predicting the outcome of patients with soft tissue sarcoma. Cancer. 2002;94(1):172-180. doi:10.1002\/cncr.10213.<\/li>\n
  42. Callegaro D, Chiechi A, Zamboni G, et al. The role of radiation therapy in the treatment of soft tissue sarcomas: A retrospective study of 1065 patients. Cancer. 1996;78(3):561-567. doi:10.1002\/(SICI)1097-0142(19960801)78:3<561::AID-CNCR10>3.0.CO;2-N.<\/li>\n
  43. Huang J, Jang JK, Chen L, et al. The role of chemotherapy in advanced or metastatic soft tissue sarcoma. Oncol Lett. 2016;12(2):913-920. doi:10.3892\/ol.2016.4737.<\/li>\n
  44. Haas RL, van Coevorden F, Molenaar WM, et al. Multimodality treatment in soft tissue sarcomas. Ann Oncol. 2002;13(4):413-419. doi:10.1093\/annonc\/mdf058.<\/li>\n
  45. Young RJ, Brown NJ, Reed MW, et al. Soft-tissue sarcomas: Current treatment and future perspectives. Sarcoma. 2005;2005(2):122-132. doi:10.1155\/2005\/758051.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    Sarcoma de tejidos blandos con invasi\u00f3n vascular Autora principal: Beatriz Matar\u00edn Mart\u00edn Vol. XX; n\u00ba 08; 369<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[176],"tags":[],"class_list":["post-80756","post","type-post","status-publish","format-standard","hentry","category-oncologia","no-featured-image-padding"],"acf":[],"yoast_head":"\nSarcoma de tejidos blandos con invasi\u00f3n vascular<\/title>\n<meta name=\"description\" content=\"Sarcoma de tejidos blandos con invasi\u00f3n vascular Autora principal: Beatriz Matar\u00edn Mart\u00edn Vol. XX; n\u00ba 08; 369 Soft tissue sarcoma with vascular invasion\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Redacci\u00f3n Revista\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"10 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"ScholarlyArticle\",\"@id\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/\"},\"author\":{\"name\":\"Redacci\u00f3n Revista\",\"@id\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#\/schema\/person\/aff35293bfdd1e8bb11bc1d216ac2c6e\"},\"headline\":\"Sarcoma de tejidos blandos con invasi\u00f3n vascular\",\"datePublished\":\"2025-04-23T15:33:49+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/\"},\"wordCount\":2157,\"publisher\":{\"@id\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#organization\"},\"articleSection\":[\"Oncolog\u00eda\"],\"inLanguage\":\"es\"},{\"@type\":[\"WebPage\",\"ItemPage\"],\"@id\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/\",\"url\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/\",\"name\":\"Sarcoma de tejidos blandos con invasi\u00f3n vascular\",\"isPartOf\":{\"@id\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#website\"},\"datePublished\":\"2025-04-23T15:33:49+00:00\",\"description\":\"Sarcoma de tejidos blandos con invasi\u00f3n vascular Autora principal: Beatriz Matar\u00edn Mart\u00edn Vol. XX; n\u00ba 08; 369 Soft tissue sarcoma with vascular invasion\",\"breadcrumb\":{\"@id\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/#breadcrumb\"},\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Inicio\",\"item\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Oncolog\u00eda\",\"item\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/publicaciones\/oncologia\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Sarcoma de tejidos blandos con invasi\u00f3n vascular\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#website\",\"url\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/\",\"name\":\"Revista Electr\u00f3nica de PortalesMedicos.com\",\"description\":\"ISSN 1886-8924 - Publicaci\u00f3n de art\u00edculos, casos cl\u00ednicos, etc. de Medicina, Enfermer\u00eda y Ciencias de la Salud\",\"publisher\":{\"@id\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#organization\"},\"alternateName\":\"Revista de PortalesMedicos\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"es\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#organization\",\"name\":\"Revista Electr\u00f3nica de Portales Medicos.com\",\"alternateName\":\"Revista de PortalesMedicos\",\"url\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/wp-content\/uploads\/logorevista_negro.jpg\",\"contentUrl\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/wp-content\/uploads\/logorevista_negro.jpg\",\"width\":199,\"height\":65,\"caption\":\"Revista Electr\u00f3nica de Portales Medicos.com\"},\"image\":{\"@id\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#\/schema\/person\/aff35293bfdd1e8bb11bc1d216ac2c6e\",\"name\":\"Redacci\u00f3n Revista\",\"sameAs\":[\"https:\/\/x.com\/portalesmedicos\"],\"url\":\"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/author\/pmedadmin\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Sarcoma de tejidos blandos con invasi\u00f3n vascular","description":"Sarcoma de tejidos blandos con invasi\u00f3n vascular Autora principal: Beatriz Matar\u00edn Mart\u00edn Vol. XX; n\u00ba 08; 369 Soft tissue sarcoma with vascular invasion","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/","twitter_misc":{"Escrito por":"Redacci\u00f3n Revista","Tiempo de lectura":"10 minutos"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"ScholarlyArticle","@id":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/#article","isPartOf":{"@id":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/"},"author":{"name":"Redacci\u00f3n Revista","@id":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#\/schema\/person\/aff35293bfdd1e8bb11bc1d216ac2c6e"},"headline":"Sarcoma de tejidos blandos con invasi\u00f3n vascular","datePublished":"2025-04-23T15:33:49+00:00","mainEntityOfPage":{"@id":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/"},"wordCount":2157,"publisher":{"@id":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#organization"},"articleSection":["Oncolog\u00eda"],"inLanguage":"es"},{"@type":["WebPage","ItemPage"],"@id":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/","url":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/","name":"Sarcoma de tejidos blandos con invasi\u00f3n vascular","isPartOf":{"@id":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#website"},"datePublished":"2025-04-23T15:33:49+00:00","description":"Sarcoma de tejidos blandos con invasi\u00f3n vascular Autora principal: Beatriz Matar\u00edn Mart\u00edn Vol. XX; n\u00ba 08; 369 Soft tissue sarcoma with vascular invasion","breadcrumb":{"@id":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/#breadcrumb"},"inLanguage":"es","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/sarcoma-de-tejidos-blandos-con-invasion-vascular\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Inicio","item":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/"},{"@type":"ListItem","position":2,"name":"Oncolog\u00eda","item":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/publicaciones\/oncologia\/"},{"@type":"ListItem","position":3,"name":"Sarcoma de tejidos blandos con invasi\u00f3n vascular"}]},{"@type":"WebSite","@id":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#website","url":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/","name":"Revista Electr\u00f3nica de PortalesMedicos.com","description":"ISSN 1886-8924 - Publicaci\u00f3n de art\u00edculos, casos cl\u00ednicos, etc. de Medicina, Enfermer\u00eda y Ciencias de la Salud","publisher":{"@id":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#organization"},"alternateName":"Revista de PortalesMedicos","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"es"},{"@type":"Organization","@id":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#organization","name":"Revista Electr\u00f3nica de Portales Medicos.com","alternateName":"Revista de PortalesMedicos","url":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/","logo":{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#\/schema\/logo\/image\/","url":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/wp-content\/uploads\/logorevista_negro.jpg","contentUrl":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/wp-content\/uploads\/logorevista_negro.jpg","width":199,"height":65,"caption":"Revista Electr\u00f3nica de Portales Medicos.com"},"image":{"@id":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/#\/schema\/person\/aff35293bfdd1e8bb11bc1d216ac2c6e","name":"Redacci\u00f3n Revista","sameAs":["https:\/\/x.com\/portalesmedicos"],"url":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/author\/pmedadmin\/"}]}},"views":602,"_links":{"self":[{"href":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/wp-json\/wp\/v2\/posts\/80756","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/wp-json\/wp\/v2\/comments?post=80756"}],"version-history":[{"count":1,"href":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/wp-json\/wp\/v2\/posts\/80756\/revisions"}],"predecessor-version":[{"id":80758,"href":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/wp-json\/wp\/v2\/posts\/80756\/revisions\/80758"}],"wp:attachment":[{"href":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/wp-json\/wp\/v2\/media?parent=80756"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/wp-json\/wp\/v2\/categories?post=80756"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.revista-portalesmedicos.com\/revista-medica\/wp-json\/wp\/v2\/tags?post=80756"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}