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Implicaciones genéticas en la cardiopatía familiar precoz

La identificación de un factor de riesgo cardiovascular a la ocurrencia de un evento coronario en una persona menor de 60 años debe indicar la necesidad urgente de una intervención activa en sus niños, aun cuando ellos no manifiestan resultados anormales, para reducir el riesgo coronario en el futuro. Muy pocos estudios han evaluado el impacto de intervenciones educativas en los miembros familiares de pacientes con enfermedades coronarias, y la mayoría de ellas se enfocaron en intervenciones de estilo de vida. Pero todos estos estudios mostraron efectos positivos prometedores con la intervención en los factores de riesgo tradicionales entre los miembros familiares. Adicionalmente, los cambios dietéticos, los ejercicios físicos, y las intervenciones sobre la tensión arterial, tienden a mejorar el perfil genético de estos niños, el comienzo debe ser precoz, y las medidas deben continuarse por largos periodos de tiempo, pues el riesgo puede persistir, indicando que la intervención debe ser continuada y sostenida para reducir factores de riesgo y obtener adhesión a los medicamentos.

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