Linfoma no Hodgkin

Dexametasona 40 mg/día d1 -4, 11-14

GCSF 5μ/Kg/día/SC d 5-12

Profilaxis del sistema nervioso central (SNC) (terapia intratecal)

Ciclo B

Rituximab 375 mg vía intravenosa (EV) d0

Metotrexate 1 gramo vía intravenosa (EV)/inf 24h d1

Leucovorina 12 horas post inf mtx, luego 12 mg/ c6h x 8 dosis. d2-3

Ara-C 12 g DT/3 gramos cada 12 horas 4 dosis d2-3

GCSF 5 μ/Kg/SC d5-12

Mantenimiento (POMP)

Puritenol 100mg VO OD x 21día

Oncovin 2 mg/día

Metotrexate 20-50mg/IM/semanal

Prednisona 40 mg vía oral x d1

8 ciclos alternos A y B


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